I don’t know if anyone will be able to relate, but my big toes do a funny thing when I walk long distances for a couple of days. They end up slightly folding in under my second toe which eventually creates a blister on the inside of my big toe. I’ve tried taping my big toe, but the chafing ends up causing a blister on the second toe.
The solution came after visiting Drifters. I spotted a pair of Injinji liner toe-socks. I bought a pair to try out and after my first multi-day hike without any foot discomfort AT ALL I went back and bought another two pairs.
They have the added benefit of being a liner sock which allows your foot to move inside your thicker hiking sock. This reduces friction on your skin and minimizes the risk of blisters overall.
You can get them from Drifters and Sportsmans Warehouse I think.